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Tiamulin 98% Cas: 125-65-5

Short Description:

Catalog Number: XD91893
Cas: 125-65-5
Molecular Formula: C22H34O5 
Molecular Weight: 378.5
Availability: In Stock 
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Product Detail

Product Tags

Catalog Number XD91893
Product Name Tiamulin 98% 
CAS 125-65-5
Molecular Formula C22H34O5 
Molecular Weight 378.5
Storage Details -20°C
Harmonized Tariff Code 2918199090

 

Product Specification

Appearance White powder
Assay 99% min
Melting point  170-1710C
alpha  D24 +20° (c = 3 in abs ethanol)
Boiling point  482.8±45.0 °C(Predicted)
density  1.15±0.1 g/cm3(Predicted)
solubility  DMSO: >10mg/mL (warmed)
pka 12.91±0.10(Predicted)
optical activity [α]/D +30 to +40° (c=1; CH2Cl2)

 

Pleuromutilin is a diterpene produced by several species of basidomycete, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin.
Pleuromutilins such as tiamulin and valnemulin have been used for some time in veterinary medicine to treat swine infections. More recently a semisynthetic pleuromutilin, retapamulin, has been introduced as a topical treatment for Gram-positive infections in humans. Pleuromutilins inhibit the peptidyl transferase activity of the bacterial 50S ribosomal subunit by binding to the A site.


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    Tiamulin 98% Cas: 125-65-5