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Strontium ranelate is a medication that has been used in the treatment of osteoporosis, a condition characterized by low bone mass and structural deterioration of bone tissue, leading to an increased risk of fractures. It consists of strontium, a metallic element, and ranelic acid, a synthetic organic compound.One of the main mechanisms of action of strontium ranelate is its dual effect on bone remodeling. It both decreases bone resorption, the process by which old bone tissue is broken down, and increases bone formation, the process by which new bone tissue is synthesized. By modulating these processes, strontium ranelate helps to restore the balance between bone resorption and formation, ultimately leading to an increase in bone mineral density and a reduction in fracture risk.Clinical studies have shown that strontium ranelate can effectively reduce the risk of vertebral and non-vertebral fractures in postmenopausal women with osteoporosis. It has also been shown to improve bone strength and reduce the risk of fractures in men with osteoporosis. The medication is typically administered orally in the form of granules or tablets.However, it is worth noting that the use of strontium ranelate has been associated with certain safety concerns. In 2014, the European Medicines Agency (EMA) restricted the use of strontium ranelate due to an increased risk of cardiovascular events, particularly in individuals with a history of cardiovascular disease. As a result, strontium ranelate is now generally prescribed only when other treatment options for osteoporosis are considered unsuitable.It is important to consult with a healthcare professional for guidance on the appropriate use of strontium ranelate, as well as to discuss potential risks and benefits based on individual medical history and condition. Ongoing research continues to assess the safety profile and effectiveness of strontium ranelate, as well as to explore alternative treatment options for osteoporosis.In conclusion, strontium ranelate is a medication used in the treatment of osteoporosis. Through its dual effect on bone remodeling, strontium ranelate helps to increase bone mineral density and reduce the risk of fractures. However, due to safety concerns, its use is now limited and carefully considered in individuals with osteoporosis. Regular monitoring and consultation with healthcare professionals are essential for optimal management of this condition.