Sodiumcyanoborohydride CAS:25895-60-7
Catalog Number | XD96002 |
Product Name | Sodiumcyanoborohydride |
CAS | 25895-60-7 |
Molecular Formula | CH3BNNa |
Molecular Weight | 62.84 |
Storage Details | Ambient |
Product Specification
Appearance | White powder |
Assay | 99% min |
Sodium cyanoborohydride, often abbreviated as NaBH3CN, is a powerful reducing agent commonly used in organic synthesis. It exhibits different effects compared to sodium triacetoxyborohydride, and its unique properties make it useful in a variety of applications.One of the main effects of sodium cyanoborohydride is its selective reduction of imines to amines. Imines are commonly formed from the reaction of aldehydes or ketones with primary amines. Sodium cyanoborohydride can efficiently reduce these imines, converting them back to the corresponding amines in high yields. This reduction process is particularly useful in the synthesis of pharmaceuticals, as amines are essential building blocks for many drugs.Moreover, sodium cyanoborohydride is effective in reducing aldehydes and ketones to their respective alcohols. It provides a milder and more controlled reduction compared to other reducing agents such as sodium borohydride. This selectivity allows for the reduction of carbonyl groups without affecting other sensitive functional groups that may be present in the molecule. This feature is especially advantageous in complex organic synthesis.Another significant effect of sodium cyanoborohydride is its ability to reduce nitriles to primary amines. Nitriles are organic compounds containing a carbon-nitrogen triple bond. Sodium cyanoborohydride can break this triple bond and replace the nitrogen with a hydrogen atom, resulting in the formation of primary amines. This reduction process is essential in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals.Furthermore, sodium cyanoborohydride displays stability in a wide range of reaction conditions and solvents. It is compatible with both acidic and basic conditions, making it versatile and adaptable for various reaction systems. This stability and versatility contribute to its wide application in the synthesis of complex organic molecules.It is important to note that sodium cyanoborohydride, like other reducing agents, can react violently or release toxic gases if mishandled or inappropriately used. Precautions should be taken to ensure proper handling, storage, and disposal.In summary, sodium cyanoborohydride is a powerful reducing agent with significant effects in organic synthesis. Its selectivity in reducing imines, carbonyl groups, and nitriles makes it a valuable tool for the production of amines, alcohols, and other functional groups. Its stability in various reaction conditions further enhances its versatility. However, caution must be exercised when working with this compound to ensure safety and prevent any potential hazards.