(R)-3-Quinuclinol CAS: 25333-42-0
Catalog Number | XD93700 |
Product Name | (R)-3-Quinuclinol |
CAS | 25333-42-0 |
Molecular Formula | C7H13NO |
Molecular Weight | 127.18 |
Storage Details | Ambient |
Product Specification
Appearance | White powder |
Assay | 99% min |
(R)-3-Quinuclidinol, also known as (R)-(1-azabicyclo[2.2.2]octan-3-ol) or quinuclidin-3-ol, is a chiral organic compound closely related to its enantiomer, (S)-3-Quinuclidinol. It exhibits a bicyclic structure comprising a quinuclidine ring fused to a hydroxyl group. This compound offers a wide range of potential applications in pharmaceutical, chemical, and synthetic organic chemistry due to its structural uniqueness and properties.One of the key uses of (R)-3-Quinuclidinol is as a chiral building block in organic synthesis. The presence of a chiral center in this compound enables it to serve as a starting material for the synthesis of various chiral compounds. Asymmetric transformations of the hydroxyl group can be carried out to introduce chirality into other molecules, thereby enabling the production of enantiomerically pure compounds with specific biological activities or desired properties.In medicinal chemistry, (R)-3-Quinuclidinol holds considerable interest because of its potential as a chiral auxiliary in the synthesis of pharmaceutical agents. It can be employed to enhance the stereochemistry and improve the biological activity of drugs. Integration of the quinuclidinol moiety into drug molecules can lead to enhanced receptor selectivity, binding affinity, and metabolic stability.Additionally, (R)-3-Quinuclidinol has been explored for its potential applications in the synthesis of alkaloids and other natural products. The quinuclidine scaffold is commonly found in various alkaloids, some of which possess intriguing biological activities such as anticholinergic and antiarrhythmic effects. Consequently, (R)-3-Quinuclidinol can serve as a valuable precursor for the production of such natural products.Furthermore, (R)-3-Quinuclidinol exhibits potential utility in catalysis and asymmetric synthesis. It can be employed as a ligand, catalyst, or resolving agent for the generation of enantiomerically pure compounds, particularly in reactions involving amines or other chiral compounds. The presence of the quinuclidinol moiety provides distinctive interactions and stereochemical control, facilitating the production of complex molecules with high stereoselectivity.It is crucial to handle and use (R)-3-Quinuclidinol with care, following appropriate safety guidelines and protocols. Adequate storage, handling, and disposal methods should be adopted to promote safety and minimize potential hazards.In summary, (R)-3-Quinuclidinol is a versatile compound with applications in organic synthesis, medicinal chemistry, catalysis, and the production of alkaloids and natural products. Its chiral nature and unique structural characteristics make it an invaluable building block for the synthesis of enantiomerically pure compounds with diverse biological activities and properties. Further research and exploration of its potential are instrumental in unlocking its full scope of applications across various fields.