China Professional China Hatu - Methyl 1,2,3,4-tetra-O-acetyl-B-D-glucuronate Cas:7355-18-2 98% – XD BIOCHEM Manufacturer and Supplier

Professional China Hatu - Methyl 1,2,3,4-tetra-O-acetyl-B-D-glucuronate Cas:7355-18-2 98% – XD BIOCHEM

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Professional China Hatu - Methyl 1,2,3,4-tetra-O-acetyl-B-D-glucuronate Cas:7355-18-2 98% – XD BIOCHEM Detail:

Catalog Number	XD90029
Product Name	methyl 1,2,3,4-tetra-O-acetyl-B-D-glucuronate
CAS	7355-18-2
Molecular Formula	C15H20O11
Molecular Weight	376.31
Storage Details	2-8 °C
Harmonized Tariff Code	29389090

Product Specification

Appearance	White to Almost white powder to crystal
Assay	98%

Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate has been used in a study to assess design and synthesis of a water-soluble glucuronide derivatives of camptothecin for cancer prodrμg monotherapy and antibody-directed enzyme prodrμg therapy. It has also been used in a study to investigate the synthesis and role of glycosylthio heterocycles in carbohydrate chemistry.

Synthesis of derivatives of pentopyranic acid

N4-Benzoylcytosine 1-(methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate) has been obtained with a yield of 70% by the glycosylation of the trimethylsilyl derivative of N4-benzoylcytosine with methyl 1,2,3,4-tetra-O-acetyl-β-D-glucopyranuronate in the presence of three equivalents of SnCl4 as condensing agent. Cytosine 1-(β-D-glucopyranosiduronamide) (IV) — the amide of pentopyranic acid — has been synthesized in practically quantitative yield by the ammonolysis of the nucleoside (I).

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