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PHENYL-1-THIO-β-D-GALACTOPYRANOSIDE Cas:16758-34-2 95% White powder

Short Description:

Catalog Number: XD90049
Cas: 16758-34-2
Molecular Formula: C12H16O5S
Molecular Weight: 272.32
Availability: In Stock
Price:
Prepack: 5g USD80
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Product Detail

Product Tags

Catalog Number XD90049
Product Name PHENYL-1-THIO-β-D-GALACTOPYRANOSIDE
CAS 16758-34-2
Molecular Formula C12H16O5S
Molecular Weight 272.32
Storage Details Ambient

Product Specification

Appearance White powder
Assay 95% min
storage Temp. 2-8°C
optical Activity [α]22/D -48.0°,c = 0.5%
Mp 93-98 °C

Binding of substituted phenyl 1-thio-β-D-galactopyranosides to β-D-galactosidase from e.

The binding of a series of substituted phenyl 1-thio-β-D-galactopyranosides to the active site ofβ-D-galactosidase from E. coli has been investigated. The inhibition constants and the standard free energy of transfer ΔG°(K1) were compared with the partition coeficients and ΔG° (1-octanol) values of these inhibitor molecules in a model 1-octanol-water system. All of the evidence available suggests that the aglycon group of the inhibitor is bound to the active site unspecific, hydrophobic forces. Correlations between ΔG° (K1) and ΔG° (1-octanol) could not be found for the whole series, but only for simpler sub-series. Probably, the octanol system is too incomplete a model for the hydrophobic region in the active site ofβ-D-galactosidase.


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    PHENYL-1-THIO-β-D-GALACTOPYRANOSIDE Cas:16758-34-2 95% White powder