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Vialox, or Pentapeptide-3, is a synthetic peptide that acts on a different part of the neuromuscular junction. As a competitive antagonist at nicotinic acetylcholine receptors, Vialox prevents the sodium influx required for muscle fibers to depolarize and contract. Within one minute of treatment, muscle contracts can be reduced by up to 71%, and 58% of muscle fibers are still immotile two hours later. Vialox can prevent wrinkles from getting deeper due to muscle contractions. In one study, Vialox used twice a day for 28 days resulted in a nearly 50% reduction in wrinkle depth and roughness. It can be used at concentrations of 0.05%–0.3% to treat facial wrinkles and tighten skin.