N,N’-Dicyclohexylcarbodiimide,DCC CAS:538-75-0
Catalog Number | XD95876 |
Product Name | N,N’-Dicyclohexylcarbodiimide,DCC |
CAS | 538-75-0 |
Molecular Formula | C13H22N2 |
Molecular Weight | 206.33 |
Storage Details | Ambient |
Product Specification
Appearance | White powder |
Assay | 99% min |
N,N’-Dicyclohexylcarbodiimide (DCC) is a chemical compound commonly used in organic synthesis as a coupling reagent. Here are some key points about its effects:Coupling Reagent: DCC is primarily used as a coupling reagent in organic chemistry to facilitate the formation of amide bonds between carboxylic acids and amines. It acts by activating the carboxylic acid moiety, allowing it to react more efficiently with an amine to form the desired amide product. This coupling reaction is widely employed in peptide synthesis and the assembly of complex organic molecules.Dehydration Agent: DCC also acts as a dehydrating agent in organic reactions. It is capable of removing water molecules from a reaction mixture, which is essential for certain reactions that require anhydrous conditions. By eliminating water, DCC promotes the formation of desired products and helps avoid unwanted side reactions.Role in Protecting Groups: DCC can be employed in the introduction and removal of various protecting groups in organic synthesis. Protecting groups are temporary modifications that shield functional groups from unwanted reactions during certain steps of a synthetic pathway. DCC is often used in conjunction with protecting groups, such as the formation of a carbonyl group transformation, to control the selectivity and reactivity of desired reactions.Side Effects and Safety Considerations: While DCC is widely used in organic synthesis, it is important to note that it can have some potential side effects. DCC is known to be highly toxic if ingested or inhaled and can cause skin and eye irritation upon contact. Proper safety precautions, including the use of protective gloves, goggles, and a fume hood, should be followed when handling DCC. Furthermore, it is crucial to handle and store DCC in a well-ventilated and controlled environment to minimize the risk of exposure.In summary, N,N’-Dicyclohexylcarbodiimide (DCC) is a versatile chemical used as a coupling reagent and dehydrating agent in organic synthesis. Its ability to facilitate amide bond formation and remove water molecules makes it a valuable tool in peptide synthesis and other organic transformations. However, caution must be exercised when handling DCC due to its toxicity and potential side effects. Following appropriate safety measures is crucial to ensure safe usage of this compound in the laboratory.