N-BOC-4-0xo-L-Proline CAS: 84348-37-8
Catalog Number | XD94135 |
Product Name | N-BOC-4-0xo-L-Proline |
CAS | 84348-37-8 |
Molecular Formula | C10H15NO5 |
Molecular Weight | 229.23 |
Storage Details | Ambient |
Product Specification
Appearance | White powder |
Assay | 99% min |
N-Boc-4-oxo-L-proline, also known as N-Boc-pyrroline-2-carboxylic acid, is an important chemical compound widely used in organic synthesis and pharmaceutical research. It plays a significant role in the development of various biologically active molecules and drug discovery efforts.One of the key applications of N-Boc-4-oxo-L-proline is its use as a building block in peptide synthesis. Peptides are essential molecules involved in a wide range of biological processes and have gained immense importance in drug development. N-Boc-4-oxo-L-proline serves as a versatile precursor for the synthesis of peptide analogs and modified peptides. It provides a strategic point for introducing functional groups or modifications to improve metabolic stability, enhance membrane permeability, or increase receptor binding affinity. By incorporating N-Boc-4-oxo-L-proline in peptide synthesis, researchers can design and create novel peptide-based therapeutics with improved properties.Moreover, N-Boc-4-oxo-L-proline finds application in the construction of diverse heterocyclic compounds. Heterocycles, which are organic compounds containing at least one ring structure with atoms other than carbon, are key components of many drugs and biologically active molecules. N-Boc-4-oxo-L-proline acts as a precursor for the synthesis of different heterocyclic scaffolds, allowing fine-tuning of their properties for specific applications, such as anticancer, antibacterial, or antiviral agents.The N-Boc protecting group in N-Boc-4-oxo-L-proline plays a crucial role in its utility. It provides stability during synthetic processes, preventing undesired reactions and ensuring high yields. The Boc group can easily be removed under mild conditions, revealing the free amino acid or allowing further modifications. This flexibility makes N-Boc-4-oxo-L-proline a valuable tool in organic synthesis, enabling chemists to manipulate and transform the compound in desired ways.Furthermore, N-Boc-4-oxo-L-proline is often employed in the development of peptidomimetics. Peptidomimetics are chemical compounds that mimic the structural and functional properties of peptides, offering advantages such as enhanced stability and bioavailability. N-Boc-4-oxo-L-proline serves as a key building block in the synthesis of peptidomimetics, allowing the design of compounds with similar biological activities to peptides but with potentially improved drug-like properties.In summary, N-Boc-4-oxo-L-proline is a versatile compound extensively utilized in organic synthesis and pharmaceutical research. Its role in peptide synthesis, heterocyclic compound construction, and peptidomimetic development underscores its importance in drug discovery and development. With its wide range of applications and versatility, N-Boc-4-oxo-L-proline is a valuable asset in the quest for novel therapeutics and biologically active molecules.