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Manufacturing Companies for Rituxan - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM

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Our pursuit and firm aim should be to "Always fulfill our buyer requirements". We carry on to produce and structure top-quality excellent solutions for equally our aged and new consumers and accomplish a win-win prospect for our consumers as well as us for Mopso Sodium Salt, Popso, 7365-44-8, Good quality is the key factor for the company to stand out from other competitors. Seeing is Believing, want more information? Just trial on its products!
Manufacturing Companies for Rituxan - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM Detail:

Catalog Number XD90291
Product Name D-Valine

CAS

640-68-6

Molecular Formula

C5H11NO2

Molecular Weight

117.14634
Storage Details Room Temp

Harmonized Tariff Code

29224995

 

Product Specification

Assay 99%
Appearance White powder
Density 1.2000 (estimate)
Melting point >295 °C (subl.) (lit.)
Boiling point 213.6 °C at 760 mmHg
Flash point 83℃
Refractive index -27 ° (C=8, 6mol/L HCl)
Solubility 56 g/L (20°C)
Water solubility 56 g/L (20 ºC)
PSA 63.32000
LogP 0.75460
Specific rotation -27.5 º (c=5, 5N HCl)
Optical activity [α]23/D −32.0 to −24.0°, c = 8 in 6 M HCl

 

Women with antiphospholipid syndrome (APS) are at increased risk of recurrent pregnancy loss (RPL) and preeclampsia. Antiphospholipid antibodies (aPL) directly alter trophoblast function. Treatment with low molecular weight heparin (LMWH) reduces the risk of RPL but not preeclampsia. Moreover, LMWH stimulates trophoblast sFlt-1 release, an anti-angiogenic factor associated with preeclampsia. Since vitamin D deficiency is associated with APS and preeclampsia, this study sought to determine the effect of vitamin D on trophoblast function in the setting of aPL and LMWH.A human first trimester trophoblast cell line (HTR8) and primary trophoblast cultures were treated with or without aPL in the presence and absence of vitamin D, LMWH or both. Trophoblast secretion of inflammatory cytokines and angiogenic factors were measured by ELISA.Vitamin D alone or in combination with LMWH attenuated the aPL-induced trophoblast inflammatory response in the HTR8 cells and primary cultures. While vitamin D did not have any impact on aPL-mediated modulation of angiogenic factors in the primary trophoblast, it significantly inhibited LMWH-induced sFlt-1 release.LMWH in combination with vitamin D may be more beneficial than single-agent therapy by preventing aPL-induced trophoblast inflammation and reversing LMWH-induced sFlt-1 secretion.


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We take "customer-friendly, quality-oriented, integrative, innovative" as objectives. "Truth and honesty" is our administration ideal for Manufacturing Companies for Rituxan - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM , The product will supply to all over the world, such as: Azerbaijan, Eindhoven, Kenya, With a wide range, good quality, reasonable prices and stylish designs, our products are extensively used in public placesand other industries. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success!
  • The factory technical staff not only have high level of technology, their English level is also very good, this is a great help to technology communication.
    5 Stars By Sara from Mozambique - 2017.07.07 13:00
    Adhering to the business principle of mutual benefits, we have a happy and successful transaction, we think we will be the best business partner.
    5 Stars By Esther from Afghanistan - 2018.09.08 17:09
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    Manufacturing Companies for Rituxan - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM