page_banner

Products

L-Cysteine CAS:52-90-4 98-101% White crystalline powder

Short Description:

Catalog Number: XD90321
Cas: 52-90-4
Molecular Formula: HSCH2CH(NH2)CO2H
Molecular Weight: 121.16
Availability: In Stock
Price:  
Prepack: 100g USD10
Bulk Pack: Request Quote

 

 

 

 

 


Product Detail

Product Tags

Catalog Number XD90321
Product Name L-Cysteine
CAS 52-90-4
Molecular Formula HSCH2CH(NH2)CO2H
Molecular Weight 121.16
Storage Details 2 to 8 °C
Harmonized Tariff Code 29309013

 

Product Specification

Appearance White crystalline powder
Assay 98.0% - 101.0%
Specific rotation +8.3°~ +9.5°
pH 4.5 ~ 5.5
SO4 0.03% max
Fe 10ppm max
Loss on Drying 0.5% max
Residue on Ignition 0.1% max
NH4 0.02% max
AS2O3 1ppm max
Cl ≤0.2%
Heavy metals (as Pb) 10ppm max
State of Solution 95.0% min

 

Iron-sulfur clusters function as cofactors of a wide range of proteins, with diverse molecular roles in both prokaryotic and eukaryotic cells. Dedicated machineries assemble the clusters and deliver them to the final acceptor molecules in a tightly regulated process. In the prototypical Gram-negative bacterium Escherichia coli, the two existing iron-sulfur cluster assembly systems, iron-sulfur cluster (ISC) and sulfur assimilation (SUF) pathways, are closely interconnected. The ISC pathway regulator, IscR, is a transcription factor of the helix-turn-helix type that can coordinate a [2Fe-2S] cluster. Redox conditions and iron or sulfur availability modulate the ligation status of the labile IscR cluster, which in turn determines a switch in DNA sequence specificity of the regulator: cluster-containing IscR can bind to a family of gene promoters (type-1) whereas the clusterless form recognizes only a second group of sequences (type-2). However, iron-sulfur cluster biogenesis in Gram-posi tive bacteria is not so well characterized, and most organisms of this group display only one of the iron-sulfur cluster assembly systems. A notable exception is the unique Gram-positive dissimilatory metal reducing bacterium Thermincola potens, where genes from both systems could be identified, albeit with a diverging organization from that of Gram-negative bacteria. We demonstrated that one of these genes encodes a functional IscR homolog and is likely involved in the regulation of iron-sulfur cluster biogenesis in T. potens. Structural and biochemical characterization of T. potens and E. coli IscR revealed a strikingly similar architecture and unveiled an unforeseen conservation of the unique mechanism of sequence discrimination characteristic of this distinctive group of transcription regulators.


  • Previous:
  • Next:

  • Close

    L-Cysteine CAS:52-90-4 98-101% White crystalline powder