Glycine benzyl ester p-toluenesulfonate salt CAS: 1738-76-7
Catalog Number | XD93848 |
Product Name | Glycine benzyl ester p-toluenesulfonate salt |
CAS | 1738-76-7 |
Molecular Formula | C16H19NO5S |
Molecular Weight | 337.39 |
Storage Details | Ambient |
Product Specification
Appearance | White powder |
Assay | 99% min |
Glycine benzyl ester p-toluenesulfonate salt, also known as glycine benzyl ester tosylate, is a chemical compound with important applications in organic synthesis, specifically in peptide and pharmaceutical research.One of the primary uses of glycine benzyl ester p-toluenesulfonate salt is in the protection and activation of amino acids during peptide synthesis. Peptides are chains of amino acids linked by peptide bonds, and in order to synthesize specific peptide sequences, various protective groups are employed to prevent unwanted reactions. Glycine benzyl ester tosylate serves as a protective group for the carboxyl group of glycine, allowing for specific reactions to occur while keeping the remaining amino acids intact. This compound can be easily removed under mild conditions after the desired reactions have taken place, revealing the unprotected amino acids and resulting in the formation of the desired peptide.Furthermore, glycine benzyl ester p-toluenesulfonate salt is widely used in the synthesis of pharmaceuticals. Peptide-based drugs are gaining prominence due to their specificity and targeted action. Glycine benzyl ester tosylate enables the efficient assembly of peptide sequences that mimic naturally occurring peptides or proteins, thereby facilitating the development of novel therapeutics. Additionally, this compound can be modified to introduce other functionalities or to enhance the pharmacological properties of peptide-based drugs, such as improved stability, bioavailability, or receptor-binding affinity.Apart from peptide synthesis, glycine benzyl ester p-toluenesulfonate salt finds application in other organic reactions. It can be used as a reagent in esterification reactions, allowing for the synthesis of glycine esters or other ester derivatives. Furthermore, the tosylate group can be displaced by nucleophiles, leading to the formation of various compounds containing the glycine moiety.In summary, glycine benzyl ester p-toluenesulfonate salt is a valuable compound for peptide synthesis and pharmaceutical research. Its use as a protecting group for glycine facilitates the efficient assembly of peptides, allowing for the development of peptide-based therapeutics. Additionally, it finds application in esterification reactions and other organic transformations. With its versatility and importance in organic synthesis, glycine benzyl ester p-toluenesulfonate salt plays a crucial role in advancing the fields of peptide chemistry and drug discovery.