Fmoc-D-Lys(Boc)-OH Cas:92122-45-7
Catalog Number | XD91504 |
Product Name | Fmoc-D-Lys(Boc)-OH |
CAS | 92122-45-7 |
Molecular Formula | C26H32N2O6 |
Molecular Weight | 468.54 |
Storage Details | Ambient |
Harmonized Tariff Code | 2924299090 |
Product Specification
Appearance | white to light yellow crystal powde |
Assay | 99% min |
Melting point | 130-135 °C (dec.) |
alpha | -12 º (c=2,DMF 24 ºC) |
Boiling point | 570.69°C (rough estimate) |
density | 1.2301 (rough estimate) |
refractive index | -12 ° (C=1, DMF) |
pka | 3.88±0.21(Predicted) |
optical activity | [α]20/D 12±1°, c = 1% in DMF |
Water Solubility | Slightly soluble in water. |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Uses:It is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.
Uses:Fmoc-Lys(Boc)-OH can be used for:The solid-phase synthesis of pentasubstituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts by coupling with p-methylbenzhydrylamine (MBHA) resin.Fmoc-based peptide synthesis of bis-naphthalene diimide, a threading intercalator.Synthesis of ε-Boc-ε-(3,5-bis-trifluoromethyl-benzyl)-α-Fmoc-L-Lysine to be used as 19F NMR based screening tool.
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