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Fixed Competitive Price Plant Extract - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM

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Fixed Competitive Price Plant Extract - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM Detail:

Catalog Number XD90291
Product Name D-Valine

CAS

640-68-6

Molecular Formula

C5H11NO2

Molecular Weight

117.14634
Storage Details Room Temp

Harmonized Tariff Code

29224995

 

Product Specification

Assay 99%
Appearance White powder
Density 1.2000 (estimate)
Melting point >295 °C (subl.) (lit.)
Boiling point 213.6 °C at 760 mmHg
Flash point 83℃
Refractive index -27 ° (C=8, 6mol/L HCl)
Solubility 56 g/L (20°C)
Water solubility 56 g/L (20 ºC)
PSA 63.32000
LogP 0.75460
Specific rotation -27.5 º (c=5, 5N HCl)
Optical activity [α]23/D −32.0 to −24.0°, c = 8 in 6 M HCl

 

Women with antiphospholipid syndrome (APS) are at increased risk of recurrent pregnancy loss (RPL) and preeclampsia. Antiphospholipid antibodies (aPL) directly alter trophoblast function. Treatment with low molecular weight heparin (LMWH) reduces the risk of RPL but not preeclampsia. Moreover, LMWH stimulates trophoblast sFlt-1 release, an anti-angiogenic factor associated with preeclampsia. Since vitamin D deficiency is associated with APS and preeclampsia, this study sought to determine the effect of vitamin D on trophoblast function in the setting of aPL and LMWH.A human first trimester trophoblast cell line (HTR8) and primary trophoblast cultures were treated with or without aPL in the presence and absence of vitamin D, LMWH or both. Trophoblast secretion of inflammatory cytokines and angiogenic factors were measured by ELISA.Vitamin D alone or in combination with LMWH attenuated the aPL-induced trophoblast inflammatory response in the HTR8 cells and primary cultures. While vitamin D did not have any impact on aPL-mediated modulation of angiogenic factors in the primary trophoblast, it significantly inhibited LMWH-induced sFlt-1 release.LMWH in combination with vitamin D may be more beneficial than single-agent therapy by preventing aPL-induced trophoblast inflammation and reversing LMWH-induced sFlt-1 secretion.


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Fixed Competitive Price Plant Extract - D-Valine  Cas: 640-68-6  C5H11NO2 – XD BIOCHEM detail pictures


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With dependable high-quality method, fantastic standing and ideal purchaser assistance, the series of products produced by our firm are exported to many countries and regions for Fixed Competitive Price Plant Extract - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM , The product will supply to all over the world, such as: New Zealand, Mexico, Comoros, Our items have been obtained more and more recognition from foreign clients, and established long term and cooperative relationship with them. We`ll supply the best service for every customer and sincerely welcome friends to work with us and establish the mutual benefit together.
  • We have been cooperated with this company for many years, the company always ensure timely delivery ,good quality and correct number, we are good partners.
    5 Stars By Heather from Thailand - 2018.12.25 12:43
    Product quality is good, quality assurance system is complete, every link can inquire and solve the problem timely!
    5 Stars By Anna from Kazakhstan - 2017.09.26 12:12
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    Fixed Competitive Price Plant Extract - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM