Factory Price For Patented Drug - L-Glutamic acid CAS:56-86-0 99% White Powder – XD BIOCHEM
Factory Price For Patented Drug - L-Glutamic acid CAS:56-86-0 99% White Powder – XD BIOCHEM Detail:
Catalog Number | XD90312 |
Product Name | D-Glutamic acid |
CAS | 56-86-0 |
Molecular Formula | C5H9NO4 |
Molecular Weight | 147.13 |
Storage Details | Ambient |
Harmonized Tariff Code | 29224200 |
Product Specification
Appearance | White Crystal or Crystalline Powder |
Assay | 99% |
Specific rotation | +31.5 to +32.5° |
pH | 3.0 to 3.5 |
Loss on Drying | 0.2% max |
Iron | 10 ppm max |
AS2O3 | 1 ppm max |
Heavy metal(Pb) | 10 ppm max |
Ammonium | 0.02% max |
Other amino acids | <0.4% |
Chloride | 0.02% max. |
Residue on Ignition (Sulfated) | 0.1% max |
Sulfate (as SO4) | 0.02% max |
he EAAT2 glutamate transporter, accounts for >90% of hippocampal glutamate uptake. Although EAAT2 is predominantly expressed in astrocytes, ∼10% of EAAT2 molecules are found in axon terminals. Despite the lower level of EAAT2 expression in glutamatergic terminals, when hippocampal slices are incubated with low concentration of d-aspartate (an EAAT2 substrate), axon terminals accumulate d-aspartate as quickly as astroglia. This implies an unexplained mismatch between the distribution of EAAT2 protein and of EAAT2-mediated transport activity. One hypothesis is that (1) heteroexchange of internal substrate with external substrate is considerably faster than net uptake and (2) terminals favor heteroexchange because of high levels of internal glutamate. However, it is currently unknown whether heteroexchange and uptake have similar or different rates. To address this issue, we used a reconstituted system to compare the relative rates of the two processes in rat and mice. Net uptake was sens itive to changes in the membrane potential and was stimulated by external permeable anions in agreement with the existence of an uncoupled anion conductance. By using the latter, we also demonstrate that the rate of heteroexchange also depends on the membrane potential. Additionally, our data further suggest the presence of a sodium leak in EAAT2. By incorporating the new findings in our previous model of glutamate uptake by EAAT2, we predict that the voltage sensitivity of exchange is caused by the voltage-dependent third Na(+) binding. Further, both our experiments and simulations suggest that the relative rates of net uptake and heteroexchange are comparable in EAAT2.
Product detail pictures:
Related Product Guide:
Our primary target will be to provide our clients a serious and responsible small business relationship, supplying personalized attention to all of them for Factory Price For Patented Drug - L-Glutamic acid CAS:56-86-0 99% White Powder – XD BIOCHEM , The product will supply to all over the world, such as: Danish, Sri Lanka, Ottawa, Our staffs are rich in experience and trained strictly, with qualified knowledge, with energy and always respect their customers as the No. 1, and promise to do their best to deliver the effective and individual service for customers. The Company pays attention to maintaining and developing the long-term cooperation relationship with the customers. We promise, as your ideal partner, we'll develop a bright future and enjoy the satisfying fruit together with you, with persisting zeal, endless energy and forward spirit.
By Hulda from Brunei - 2017.01.28 18:53
Company director has very rich management experience and strict attitude, sales staff are warm and cheerful, technical staff are professional and responsible,so we have no worry about product,a nice manufacturer.
By Agustin from Hongkong - 2018.10.01 14:14