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Europe style for Mes Monohydrate - D-Luciferin Cas: 2591-17-5 99% Off-white to yellow powder nbsp BEETLE LUCIFERIN – XD BIOCHEM

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Europe style for Mes Monohydrate - D-Luciferin Cas: 2591-17-5 99% Off-white to yellow powder nbsp BEETLE LUCIFERIN – XD BIOCHEM Detail:

Catalog Number XD90248
Product Name D-Luciferin

CAS

2591-17-5

Molecular Formula

C11H8N2O3S2

Molecular Weight

280.323
Storage Details -15 to -20 °C

Harmonized Tariff Code

29342080

 

Product Specification

Water Content Max. 2.0%
Turbidity Max 2.0 NTU
Specific optical rotation -36 to -32
Appearance Off-white to yellow powder
Purity HPLC Min 99%
Molar extinction coefficient

min 17900 L/(mol cm)

 

Introduction: D-luciferin is a substrate for adenosine triphosphate (ATP)-dependent bioluminescence reaction. The principle of bioluminescence is that luciferin is oxidized by luciferase in the presence of ATP and oxygen. The chemical reaction formula is as follows: ATP+D-Luciferin+O2→Oxyluciferin+AMP+PPi+O2+Light.

Mechanism of action: The mechanism of action of D-luciferin is that under the action of ATP and luciferase, luciferin (substrate) can be oxidized to emit light. When luciferin is in excess, the number of photons produced is positively correlated with the concentration of luciferase.

Application: D-luciferin is a substrate for adenosine triphosphate (ATP)-dependent bioluminescence reactions. The bioluminescence reaction of luciferin/luciferase is often used for the detection of ATP, metabolites that can be converted into ATP (such as AMP, ADP, cAMP), and enzymes that can generate ATP (such as creatine kinase, etc.), so the bioluminescence reaction can be used. Applicable to the detection of a wide range of biological materials.

Biological Activity: D-Luciferin (Firefly luciferin) is a popular substrate for bioluminescence in the presence of ATP for use in luciferase-based bioluminescence imaging and cell-based high-throughput screening.

In vitro studies: D-luciferin reacts with luciferase, ATP and oxygen to emit light, which is detected by sensitive photographic film to visualize alkaline phosphatase-bound antibodies.

In vivo studies: use of D-luciferin substrates and firefly luciferase preserves tumor-host immune interactions in an immunocompetent mouse model with ovarian cancer, as bioluminescence programs are more sensitive to tumor growth than body weight gain instructions.


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We support our purchasers with ideal premium quality products and substantial level company. Becoming the specialist manufacturer in this sector, we've acquired rich practical working experience in producing and managing for Europe style for Mes Monohydrate - D-Luciferin Cas: 2591-17-5 99% Off-white to yellow powder nbsp BEETLE LUCIFERIN – XD BIOCHEM , The product will supply to all over the world, such as: Senegal, Austria, Doha, Besides strong technical strength, we also introduce advanced equipment for inspection and conduct strict management. All the staff of our company welcome friends both at home and abroad to come for visits and business on the basis of equality and mutual benefit. If you are interested in any of our items, please feel free to contact us for quotation and product details.
  • We are long-term partners, there is no disappointment every time, we hope to maintain this friendship later!
    5 Stars By Eden from Belgium - 2017.10.25 15:53
    This company has the idea of "better quality, lower processing costs, prices are more reasonable", so they have competitive product quality and price, that's the main reason we chose to cooperate.
    5 Stars By Janet from Brisbane - 2017.02.18 15:54
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    Europe style for Mes Monohydrate - D-Luciferin Cas: 2591-17-5 99% Off-white to yellow powder nbsp BEETLE LUCIFERIN – XD BIOCHEM