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D-Aspartic acid CAS:1783-96-6 99% White powder

Short Description:

Catalog Number: XD90316
Cas: 1783-96-6
Molecular Formula: C4H7NO4
Molecular Weight: 133.10
Availability: In Stock
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Prepack: 25g USD10
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Product Detail

Product Tags

Catalog Number XD90316
Product Name D-Aspartic acid
CAS 1783-96-6
Molecular Formula C4H7NO4
Molecular Weight 133.10
Storage Details Ambient
Harmonized Tariff Code 29224985

 

Product Specification

Appearance White powder
Assay 99%
Specific rotation -24 to -26
Heavy metals <10ppm
AS <1ppm
pH ≤0.2%
SO4 <0.02%
Fe <10ppm
Loss on Drying <0.20%
Residue on Ignition <0.10%
NH4 <0.02%
Transmittance >98%
Cl <0.02%

 

Secondary transporters are integral membrane proteins that catalyse the movement of substrate molecules across the lipid bilayer by coupling substrate transport to one or more ion gradients, thereby providing a mechanism for the concentrative uptake of substrates. Here we describe crystallographic and thermodynamic studies of Glt(Ph), a sodium (Na+)-coupled aspartate transporter, defining sites for aspartate, two sodium ions and d,l-threo-beta-benzyloxyaspartate, an inhibitor. We further show that helical hairpin 2 is the extracellular gate that controls access of substrate and ions to the internal binding sites. At least two sodium ions bind in close proximity to the substrate and these sodium-binding sites, together with the sodium-binding sites in another sodium-coupled transporter, LeuT, define an unwound alpha-helix as the central element of the ion-binding motif, a motif well suited to the binding of sodium and to participation in conformational changes that accompany ion binding and unbinding during the transport cycle.


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    D-Aspartic acid CAS:1783-96-6 99% White powder