Concanavalin A CAS:11028-71-0 Powder LECTIN FROM CONCANAVALIN A PEROXIDASE*LA BELED
Catalog Number | XD90334 |
Product Name | Concanavalin A |
CAS | 11028-71-0 |
Molecular Formula | C23H32N6O8S |
Molecular Weight | 552.60 |
Storage Details | 2 to 8 °C |
Product Specification
Appearance | White Powder |
Assay | 99% |
Flash point | 39 °C |
water soluble | Slightly soluble in water and phosfate buffered saline. |
Solubility | Slightly soluble in water. |
Concanavalin A is not blood group specific, but has affinity for terminal α-D-mannosyl and α-D-glucosyl residues. The presence of Ca2+ and Mn2+ ions is required to show activity. Concanavalin A dissociates into dimers at pH 6.5 or lower. When the pH is between 5.8 and 7.0 Chemicalbook, Concanavalin A exists in the form of tetramers; when the pH is higher than 7.0, higher aggregates are formed. Depending on the degree of polymerization, concanavalin A may exhibit mitogenic activity. Succinylation produces an active dimer that can remain in dimer form at pH above 5.6.
It is a mito-gen, which mainly stimulates T lymphocytes, agglutinates red blood cells and animal sperm, inhibits tumor cell movement, and prolongs the survival time of allogeneic transplantation. An important biochemical and immunological research reagent.