Colistin Sulfate Cas: 1264-72-8
| Catalog Number | XD92222 |
| Product Name | Colistin Sulfate |
| CAS | 1264-72-8 |
| Molecular Formula | C52H98N16O13 |
| Molecular Weight | 1155.43 |
| Storage Details | 2 to 8 °C |
| Harmonized Tariff Code | 29419000 |
Product Specification
| Appearance | White to almost white powder |
| Assay | 99% min |
| pH | 4-6 |
| Loss on Drying | <3.5% |
| Solubility | Freely soluble in water, slightly soluble in ethanol (96%), practically insoluble in acetone trichloromethane or diethyl ether |
| Sulfate | 16 - 18% |
| Specific optical rotation | -63 to -73 |
| Total Impurities | <23% |
| Sulfated ash | <1% |
| Potency (dried basis) | >19000u/mg |
1.It is a basic peptide antibiotics, mainly for the prevention and treatment of susceptible infections and promote animal growth.
2.It can be combined with the cell membrane lipoprotein phosphate free, making the cell membrane surface tension decreases, increased permeability, resulting in the cytoplasm outflow of cell death.
3.It has a strong inhibitory effect against gram-negative bacteria (particularly E. coli, Salmonella, Pseudomonas aeruginosa, Proteus and Haemophilus, etc.),has no effect on Gram-positive bacteria (Staphylococcus aureus and except hemolytic streptococcus outside) and fungi.
4. Colistin sulfate oral is difficult to absorb, less toxic, easy to cause drug residues, easy to produce drug resistance.
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