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China wholesale Iptg - 4-Nitrophenyl-alpha-D-glucopyranoside CAS:3767-28-0 99% – XD BIOCHEM

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China wholesale Iptg - 4-Nitrophenyl-alpha-D-glucopyranoside CAS:3767-28-0 99% – XD BIOCHEM Detail:

Catalog Number XD900017
Product Name 4-Nitrophenyl-alpha-D-glucopyranoside
CAS 3767-28-0
Molecular Formula C12H15NO8
Molecular Weight 301.25
Storage Details -2 to -8 °C
Harmonized Tariff Code 29400000

Product Specification

Water 0.5% max
Solubility (50mg/ml in H2O) Clear to slightly hazy, colorless to faint yellow solution
Storage -20°C, dry, dark
Assay (HPLC ) 99.0% min
Specific rotation (C=0.5, water) +215°~+221°
Appearance Off-white to light yellow Crystalline Powder

In the continuing search for safe and efficient antidiabetic drug, marine algae become important source which provide several compounds of immense therapeutic potential. Alpha-amylase, alpha-glucosidase inhibitors, and antioxidant compounds are known to manage diabetes and have received much attention recently. In the present study, four green algae (Chaetomorpha aerea, Enteromorpha intestinalis, Chlorodesmis, and Cladophora rupestris) were chosen to evaluate alpha-amylase, alpha-glucosidase inhibitory, and antioxidant activity in vitro.The phytochemical constituents of all the extracts were qualitatively determined. Antidiabetic activity was evaluated by inhibitory potential of extracts against alpha-amylase and alpha-glucosidase by spectrophotometric assays. Antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl, hydrogen peroxide (H2O2), and nitric oxide scavenging assay. Gas chromatography-mass spectrometry (GC-MS) analysis was carried out to determine the major compound responsible for its antidiabetic action.Among the various extracts screened, chloroform extract of C. aerea (IC50 – 408.9 μg/ml) and methanol extract of Chlorodesmis (IC50 – 147.6 μg/ml) showed effective inhibition against alpha-amylase. The extracts were also evaluated for alpha-glucosidase inhibition, and no observed activity was found. Methanol extract of C. rupestris showed notable free radical scavenging activity (IC50 – 666.3 μg/ml), followed by H2O2 (34%) and nitric oxide (49%). Further, chemical profiling by GC-MS revealed the presence of major bioactive compounds. Phenol, 2,4-bis (1,1-dimethylethyl) and z, z-6,28-heptatriactontadien-2-one were predominantly found in the methanol extract of C. rupestris and chloroform extract of C. aerea.Our results demonstrate that the selected algae exhibit notable alpha-amylase inhibition and antioxidant activity. Therefore, characterization of active compounds and its in vivo assays will be noteworthy.Four green algae were chosen to evaluate alpha-amylase, alpha-glucosidase inhibitory, and antioxidant activity in vitro C. aerea and Chlorodesmis showed significant inhibition against alpha-amylase, and C. rupestris showed notable free radical scavenging activityNo observed activity was found against alpha-glucosidaseGC-MS analysis of the active extracts reveals the presence of major compounds which gives an insight on the antidiabetic and antioxidant activity of these algae. Abbreviations used: DPPH: 2,2-diphenyl-1-picrylhydrazyl, BHT: Butylated hydroxytoluene, GC-MS: Gas chromatography-mass spectrometry.


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The corporate keeps towards the operation concept "scientific administration, superior quality and performance primacy, client supreme for China wholesale Iptg - 4-Nitrophenyl-alpha-D-glucopyranoside CAS:3767-28-0 99% – XD BIOCHEM , The product will supply to all over the world, such as: Juventus, Miami, Somalia, We have the best products and professional sales and technical team.With the development of our company, we are able to provide customers best products, good technical support, perfect after-sales service.
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    China wholesale Iptg - 4-Nitrophenyl-alpha-D-glucopyranoside CAS:3767-28-0 99% – XD BIOCHEM