China Supplier Daos - 5-Methylphenazinium methosulfate Cas: 299-11-6 99% Dark green to brown powder – XD BIOCHEM
China Supplier Daos - 5-Methylphenazinium methosulfate Cas: 299-11-6 99% Dark green to brown powder – XD BIOCHEM Detail:
Catalog Number | XD90224 |
Product Name | 5-Methylphenazinium methosulfate |
CAS |
299-11-6 |
Molecular Formula |
C14H14N2O4S |
Molecular Weight |
306.337 |
Storage Details | -15 to -20 °C |
Harmonized Tariff Code | 29339980 |
Product Specification
Melting Point | 158-160 °C (dec.)(lit.) |
Assay | 99% |
Form | Solid |
Appearance | Dark green to brown powder |
The n-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been shown to enhance the effect of chemotherapeutic drugs in clinical studies in cancer patients and to induce apoptotic tumor cell death in vitro. Until now, EPA and DHA have never been investigated in multiple myeloma (MM). Human myeloma cells (L363, OPM-1, OPM-2 and U266) and normal peripheral blood mononuclear cells were exposed to EPA and DHA, and effects on mitochondrial function and apoptosis, caspase-3 activation, gene expression and drug toxicity were measured. Exposure to EPA and DHA induced apoptosis and increased sensitivity to bortezomib in MM cells. Importantly, they did not affect viability of normal human peripheral mononuclear cells. Messenger RNA expression arrays showed that EPA and DHA modulated genes involved in multiple signaling pathways including nuclear factor (NF) κB, Notch, Hedgehog, oxidative stress and Wnt. EPA and DHA inhibited NFκB activity and induced apo ptosis through mitochondrial perturbation and caspase-3 activation. Our study suggests that EPA and DHA induce selective cytotoxic effects in MM and increase sensitivity to bortezomib and calls for further exploration into a potential application of these n-3 polyunsaturated fatty acids in the therapy of MM
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To continuously increase the administration process by virtue of the rule of "sincerely, good religion and excellent are the base of company development", we commonly absorb the essence of linked goods internationally, and continually build new solutions to fulfill the requires of shoppers for China Supplier Daos - 5-Methylphenazinium methosulfate Cas: 299-11-6 99% Dark green to brown powder – XD BIOCHEM , The product will supply to all over the world, such as: Paraguay, Canada, Romania, In order to meet the increasing requirement of customers both home and aboard, we will keep carrying forward the enterprise spirit of "Quality, Creativity, Efficiency and Credit" and strive to top the current trend and lead fashion. We warmly welcome you to visit our company and make cooperation.
By Quintina from Mexico - 2018.09.23 18:44
The manufacturer gave us a big discount under the premise of ensuring the quality of products, thank you very much, we will select this company again.
By Gladys from Roman - 2017.06.25 12:48