page_banner

Products

8 Year Exporter Roche Holdings - DL-Alanine CAS:302-72-7 99% – XD BIOCHEM

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

Our items are commonly identified and trusted by customers and may fulfill continuously switching economic and social wants of Tris(Hydroxymethyl)Nitromethane, Caps Sodium Salt, Process Research And Development, We have been wanting ahead to setting up cooperative associations along with you. Make sure you contact us for more data.
8 Year Exporter Roche Holdings - DL-Alanine CAS:302-72-7 99% – XD BIOCHEM Detail:

Catalog Number XD90327
Product Name DL-Alanine
CAS 302-72-7
Molecular Formula C3H7NO2
Molecular Weight 89.09
Storage Details Ambient
Harmonized Tariff Code 29224985

 

Product Specification

Catalog Number XD90327
Product Name DL-Alanine
CAS 302-72-7
Molecular Formula C3H7NO2
Molecular Weight 89.09
Storage Details Ambient
Harmonized Tariff Code 29224985

 

The effectiveness of antibiotic molecules in treating Pseudomonas aeruginosa pneumonia is reduced as a result of the dissemination of bacterial resistance. The existence of bacterial communication systems, such as quorum sensing, has provided new opportunities of treatment. Lactonases efficiently quench acyl-homoserine lactone-based bacterial quorum sensing, implicating these enzymes as potential new anti-Pseudomonas drugs that might be evaluated in pneumonia.The aim of the present study was to evaluate the ability of a lactonase called SsoPox-I to reduce the mortality of a rat P. aeruginosa pneumonia.To assess SsoPox-I-mediated quorum quenching, we first measured the activity of the virulence gene lasB, the synthesis of pyocianin, the proteolytic activity of a bacterial suspension and the formation of biofilm of a PAO1 strain grown in the presence of lactonase. In an acute lethal model of P. aeruginosa pneumonia in rats, we evaluated the effects of an early or deferred intra-tracheal treatment with SsoPox-I on the mortality, lung bacterial count and lung damage.SsoPox-I decreased PAO1 lasB virulence gene activity, pyocianin synthesis, proteolytic activity and biofilm formation. The early use of SsoPox-I reduced the mortality of rats with acute pneumonia from 75% to 20%. Histological lung damage was significantly reduced but the lung bacterial count was not modified by the treatment. A delayed treatment was associated with a non-significant reduction of mortality.These results demonstrate the protective effects of lactonase SsoPox-I in P. aeruginosa pneumonia and open the way for a future therapeutic use.


Product detail pictures:

8 Year Exporter Roche Holdings - DL-Alanine  CAS:302-72-7  99% – XD BIOCHEM detail pictures


Related Product Guide:

We keep on with the theory of "quality first, provider initially, constant improvement and innovation to meet the customers" with the management and "zero defect, zero complaints" as the standard objective. To great our company, we deliver the merchandise using the fantastic excellent at the reasonable price for 8 Year Exporter Roche Holdings - DL-Alanine CAS:302-72-7 99% – XD BIOCHEM , The product will supply to all over the world, such as: Slovenia, Ethiopia, Paraguay, Our product quality is one of the major concerns and has been produced to meet the customer's standards. "Customer services and relationship" is another important area which we understand good communication and relationships with our customers is the most significant power to run it as a long term business.
  • This company conforms to the market requirement and joins in the market competition by its high quality product, this is an enterprise that have Chinese spirit.
    5 Stars By Andrea from Seattle - 2017.04.18 16:45
    High Quality, High Efficiency, Creative and Integrity, worth having long-term cooperation! Looking forward to the future cooperation!
    5 Stars By Sandra from Wellington - 2017.10.25 15:53
    Close

    8 Year Exporter Roche Holdings - DL-Alanine CAS:302-72-7 99% – XD BIOCHEM