page_banner

Products

5-Fluoro-2′-deoxyuridine Cas:50-91-9

Short Description:

Catalog Number: XD90578
Cas: 50-91-9
Molecular Formula: C9H11FN2O5
Molecular Weight: 246.19
Availability: In Stock
Price:  
Prepack: 1g USD10
Bulk Pack: Request Quote

 


Product Detail

Product Tags

Catalog Number XD90578
Product Name 5-Fluoro-2'-deoxyuridine

CAS

50-91-9

Molecular Formula

C9H11FN2O5

Molecular Weight

246.19
Storage Details 2 to 8 °C
Harmonized Tariff Code 29349990

 

Product Specification

Appearance White to off white crystalline powder
Assay 99%
Loss on Drying ≤0.5%

 

The ability of Clostridium thermocellum to rapidly degrade cellulose and ferment resulting hydrolysis products into ethanol makes it a promising platform organism for cellulosic biofuel production via consolidated bioprocessing. Currently, however, ethanol yield is far below theoretical maximum due to branched product pathways that divert carbon and electrons towards formate, H2, lactate, acetate, and secreted amino acids. To redirect carbon and electron flux away from formate, genes encoding pyruvate:formate lyase (pflB) and PFL-activating enzyme (pflA) were deleted. Formate production in the resulting Δpfl strain was eliminated and acetate production decreased by 50 % on both complex and defined medium. The growth rate of the Δpfl strain decreased by 2.9-fold on defined medium and biphasic growth was observed on complex medium. Supplementation of defined medium with 2 mM formate restored Δpfl growth rate to 80 % of the parent strain. The role of pfl in metabolic engineering strategie s and C1 metabolism is discussed.


  • Previous:
  • Next:

  • Close

    5-Fluoro-2′-deoxyuridine Cas:50-91-9