5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde CAS: 881677-11-8
Catalog Number | XD93713 |
Product Name | 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde |
CAS | 881677-11-8 |
Molecular Formula | C16H11FN2O3S |
Molecular Weight | 330.33 |
Storage Details | Ambient |
Product Specification
Appearance | White powder |
Assay | 99% min |
5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde is a chemical compound with potential applications in medicinal chemistry and drug discovery. Its unique structure, combining a fluorophenyl group, a pyridin-3-ylsulfonyl group, and a pyrrole-3-carbaldehyde moiety, provides an opportunity for the development of diverse pharmaceutical compounds.The presence of the fluorophenyl group enhances the compound's lipophilicity, enabling it to interact effectively with hydrophobic regions of target proteins or receptors. This interaction is essential for drug molecules to bind to their targets and exert their desired effects in the body. Additionally, the fluorophenyl group can serve as a handle for further modification, allowing for the introduction of various functional groups or substitutions to optimize the compound's pharmacological properties.The pyridin-3-ylsulfonyl group is a versatile moiety that can modulate the compound's biological activity. It can act as a bioisostere, replacing other functional groups while preserving similar interactions with target proteins. Moreover, the sulfonamide linkage has been found to contribute to improved metabolic stability and pharmacokinetic properties in some compounds, making it an attractive feature for drug design.The presence of the pyrrole-3-carbaldehyde moiety adds another dimension to the compound's potential uses. Pyrrole derivatives have exhibited promising activities in various therapeutic areas, including antitumor, anti-inflammatory, and anti-infective applications. The aldehyde group, being a reactive functional group, offers opportunities for further chemical transformations, such as the formation of imines or oximes, which can expand the compound's biological diversity.Given its unique structure and potential pharmacological activities, 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde can be utilized as a starting point for medicinal chemistry research. Through modifications and derivatizations, researchers can explore its structure-activity relationships (SAR) to optimize its therapeutic activity, selectivity, and pharmacokinetic properties.Furthermore, this compound can serve as a lead compound or pharmacophore for virtual or experimental screening against target proteins in drug discovery programs. Similarly, it can be used as a building block for the synthesis of focused libraries of compounds, which can be screened for potential drug candidates in various therapeutic areas.In summary, 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde is a structurally unique compound with potential applications in medicinal chemistry and drug discovery. Its combination of the fluorophenyl, pyridin-3-ylsulfonyl, and pyrrole-3-carbaldehyde moieties offers opportunities for optimization, bioisosteric replacement, and further chemical transformations. By exploiting these features, researchers can explore its SAR, develop focused compound libraries, and contribute to the discovery of novel pharmaceuticals in various therapeutic areas.