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(4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE CAS: 189028-95-3

Short Description:

Catalog Number: XD93706
Cas: 189028-95-3
Molecular Formula: C20H20FNO4
Molecular Weight: 357.38
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Product Detail

Product Tags

Catalog Number XD93706
Product Name (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE
CAS 189028-95-3
Molecular Formula C20H20FNO4
Molecular Weight 357.38
Storage Details Ambient

 

Product Specification

Appearance White powder
Assay 99% min

 

The compound you have described, (4S)-3-[(5R)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one, is a specific chemical compound that belongs to the oxazolidinone class of molecules. Oxazolidinones have gained significant attention in the field of medicinal chemistry due to their broad-spectrum antimicrobial activity, particularly against Gram-positive bacteria.The compound's chemical structure suggests that it possesses both a phenyl group and a fluorophenyl moiety, which can confer specific physicochemical properties and potential interactions with biological targets. This compound also contains an oxazolidinone ring, which is a key structural feature responsible for its antibacterial activity.Oxazolidinones, including (4S)-3-[(5R)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one, target the bacterial 23S ribosomal RNA subunit in the bacterial ribosome. By binding to the peptidyltransferase center, these compounds inhibit the formation of a functional initiation complex and interfere with protein synthesis. This disruption leads to the inhibition of bacterial growth and eventually results in bacterial cell death.The presence of a hydroxyl group appended to the lateral chain of the oxazolidinone ring in this compound enhances its antibacterial activity by providing additional interactions with the active site of the ribosome and potentially increasing its inhibitory potency. The fluorophenyl group also contributes to the compound's overall activity by potentially enhancing its lipophilicity and improving its ability to penetrate bacterial cells and reach its target.(4S)-3-[(5R)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one, like other oxazolidinones, has demonstrated effectiveness against a broad range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium (VRE), and Streptococcus pneumoniae. However, it is important to note that further research and clinical trials are typically necessary to determine the compound's specific spectrum of activity, efficacy, and safety profile.In summary, (4S)-3-[(5R)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one is a compound belonging to the oxazolidinone class with potential antimicrobial properties against Gram-positive bacteria. Its structural features, such as the presence of a phenyl group, a fluorophenyl moiety, and an oxazolidinone ring, play crucial roles in determining its activity and potential therapeutic applications. However, further investigation and evaluation are necessary to fully understand and utilize its properties in the development of novel antibacterial agents.


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    (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE CAS: 189028-95-3