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3-Quinolinecarboxylic acid,7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo- CAS: 117528-65-1

Short Description:

Catalog Number: XD93405
Cas: 117528-65-1
Molecular Formula: C14H8ClFN2O3
Molecular Weight: 306.68
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Product Detail

Product Tags

Catalog Number XD93405
Product Name 3-Quinolinecarboxylic acid,7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-
CAS 117528-65-1
Molecular Formula C14H8ClFN2O3
Molecular Weight 306.68
Storage Details Ambient

 

Product Specification

Appearance White powder
Assay 99% min

 

3-Quinolinecarboxylic acid, 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, also known as levofloxacin, is a broad-spectrum antibiotic that is widely used in the treatment of various bacterial infections. It belongs to the fluoroquinolone class of antibiotics and exhibits potent antimicrobial activity against both Gram-positive and Gram-negative bacteria.Levofloxacin is commonly used in the management of respiratory tract infections such as bronchitis and pneumonia, as well as urinary tract infections, skin and soft tissue infections, and bacterial prostatitis. Its mechanism of action involves inhibiting bacterial DNA gyrase and topoisomerase IV enzymes, which are essential for DNA replication, repair, and recombination in bacteria. By interfering with these enzymes, levofloxacin disrupts the bacterial DNA synthesis, leading to bacterial cell death.Levofloxacin is well-absorbed orally and shows good tissue penetration, allowing it to reach high concentrations at the site of infection. This property contributes to its effectiveness against various pathogens, including those that are resistant to other antibiotics. Furthermore, levofloxacin exhibits a prolonged half-life, which allows for once-daily dosing, enhancing patient compliance and convenience.In addition to its use in the treatment of common bacterial infections, levofloxacin has also demonstrated activity against atypical pathogens like Mycoplasma pneumoniae and Legionella pneumophila. This makes it a suitable choice for treating atypical pneumonia cases. Moreover, levofloxacin has been found to be effective in the eradication of Helicobacter pylori, a bacterium associated with the development of gastritis and peptic ulcers.However, it is important to note that the use of levofloxacin should be done with caution, considering the potential for adverse effects and development of antibiotic resistance. Levofloxacin has been associated with side effects such as nausea, diarrhea, headache, and dizziness. It should not be used in individuals with a known hypersensitivity to fluoroquinolones or in certain patient populations like pregnant women, breastfeeding mothers, and children under the age of 18.In conclusion, 3-Quinolinecarboxylic acid, 7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, or levofloxacin, is a potent and widely used antibiotic for the treatment of bacterial infections. Its broad-spectrum activity, good tissue penetration, and convenient dosing regimen make it a valuable therapeutic option. However, caution must be exercised in its use, considering potential side effects and the need to combat antibiotic resistance.


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    3-Quinolinecarboxylic acid,7-chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo- CAS: 117528-65-1