2,4,5-trifluorobenzyl bromide CAS: 157911-56-3
Catalog Number | XD93373 |
Product Name | 2,4,5-trifluorobenzyl bromide |
CAS | 157911-56-3 |
Molecular Formula | C7H4BrF3 |
Molecular Weight | 225.01 |
Storage Details | Ambient |
Product Specification
Appearance | White powder |
Assay | 99% min |
The compound 2,4,5-Trifluorobenzyl bromide is an organic compound with the chemical formula C7H5BrF3. It is an aromatic compound that belongs to the class of benzyl derivatives. The compound is characterized by the presence of three fluorine atoms attached to the benzyl group and a bromine atom.One of the main applications of 2,4,5-trifluorobenzyl bromide is in organic synthesis. It can be used as a versatile building block in the preparation of various compounds. The trifluoromethyl group in the compound imparts unique reactivity and properties that can be exploited for the synthesis of complex organic molecules. For example, the compound is commonly used in the construction of fluorinated pharmaceuticals, agrochemicals, and other biologically active compounds.The reactivity of 2,4,5-trifluorobenzyl bromide can be attributed to the presence of the bromine atom. The bromine atom serves as a leaving group and enables substitution reactions where the bromine is replaced by other functional groups. This property makes the compound useful in the synthesis of diverse compounds by functionalizing the benzyl group.Additionally, the compound's highly electron-withdrawing fluorine atoms can influence the reactivity and stability of the products derived from 2,4,5-trifluorobenzyl bromide. The presence of fluorine atoms can enhance the metabolic stability of drugs and increase lipophilicity, which can affect their pharmacokinetic properties, such as their absorption and distribution in the body.2,4,5-Trifluorobenzyl bromide can also find use as a reagent or intermediate in various chemical reactions. For example, it can participate in coupling reactions, such as Suzuki-Miyaura cross-coupling, to form carbon-carbon bonds. This reaction has broad applications in pharmaceutical and agrochemical synthesis.In conclusion, 2,4,5-Trifluorobenzyl bromide is a versatile compound with applications in organic synthesis. Its trifluoromethyl group and bromine atom provide opportunities for the construction of complex molecules and functionalization of the benzyl group. The compound's reactivity and properties make it valuable for the synthesis of pharmaceuticals, agrochemicals, and other biologically active compounds. Furthermore, it can serve as a useful reagent or intermediate in various chemical reactions.