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2022 Latest Design Infectious Disease - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM

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2022 Latest Design Infectious Disease - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM Detail:

Catalog Number XD90291
Product Name D-Valine

CAS

640-68-6

Molecular Formula

C5H11NO2

Molecular Weight

117.14634
Storage Details Room Temp

Harmonized Tariff Code

29224995

 

Product Specification

Assay 99%
Appearance White powder
Density 1.2000 (estimate)
Melting point >295 °C (subl.) (lit.)
Boiling point 213.6 °C at 760 mmHg
Flash point 83℃
Refractive index -27 ° (C=8, 6mol/L HCl)
Solubility 56 g/L (20°C)
Water solubility 56 g/L (20 ºC)
PSA 63.32000
LogP 0.75460
Specific rotation -27.5 º (c=5, 5N HCl)
Optical activity [α]23/D −32.0 to −24.0°, c = 8 in 6 M HCl

 

Women with antiphospholipid syndrome (APS) are at increased risk of recurrent pregnancy loss (RPL) and preeclampsia. Antiphospholipid antibodies (aPL) directly alter trophoblast function. Treatment with low molecular weight heparin (LMWH) reduces the risk of RPL but not preeclampsia. Moreover, LMWH stimulates trophoblast sFlt-1 release, an anti-angiogenic factor associated with preeclampsia. Since vitamin D deficiency is associated with APS and preeclampsia, this study sought to determine the effect of vitamin D on trophoblast function in the setting of aPL and LMWH.A human first trimester trophoblast cell line (HTR8) and primary trophoblast cultures were treated with or without aPL in the presence and absence of vitamin D, LMWH or both. Trophoblast secretion of inflammatory cytokines and angiogenic factors were measured by ELISA.Vitamin D alone or in combination with LMWH attenuated the aPL-induced trophoblast inflammatory response in the HTR8 cells and primary cultures. While vitamin D did not have any impact on aPL-mediated modulation of angiogenic factors in the primary trophoblast, it significantly inhibited LMWH-induced sFlt-1 release.LMWH in combination with vitamin D may be more beneficial than single-agent therapy by preventing aPL-induced trophoblast inflammation and reversing LMWH-induced sFlt-1 secretion.


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To create far more benefit for customers is our company philosophy; customer growing is our working chase for 2022 Latest Design Infectious Disease - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM , The product will supply to all over the world, such as: New York, Accra, Seychelles, Hard work to keep making progress, innovation in the industry, make every effort to first-class enterprise. We try our best to build the scientific management model, to learn abundant experienced knowledge, to develop advanced production equipment and production process , to create the first-call quality goods, reasonable price , high quality of service , quick delivery , to present you create new value .
  • High Quality, High Efficiency, Creative and Integrity, worth having long-term cooperation! Looking forward to the future cooperation!
    5 Stars By Leona from Moscow - 2017.05.21 12:31
    We are really happy to find such a manufacturer that ensuring product quality at the same time the price is very cheap.
    5 Stars By Daniel Coppin from Puerto Rico - 2017.11.01 17:04
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    2022 Latest Design Infectious Disease - D-Valine Cas: 640-68-6 C5H11NO2 – XD BIOCHEM