2022 China New Design 1,4-Dithioerythritol (Dte) - 2,3,4,6-Tetra-O-benzyl-D-galactopyranose Cas:53081-25-7 White Powder 98% – XD BIOCHEM
2022 China New Design 1,4-Dithioerythritol (Dte) - 2,3,4,6-Tetra-O-benzyl-D-galactopyranose Cas:53081-25-7 White Powder 98% – XD BIOCHEM Detail:
| Catalog Number | XD90027 |
| Product Name | 2,3,4,6-Tetra-O-benzyl-D-galactopyranose |
| CAS | 53081-25-7 |
| Molecular Formula | C34H36O6 |
| Molecular Weight | 540.65 |
| Storage Details | -15 to -20 °C |
| Harmonized Tariff Code | 29400000 |
Product Specification
| Water | ≤0.5% |
| Specific rotation | +8.5-+13 |
| Purity | ≥98% |
| Appearance | White powder |
Two isomeric bicyclo[4.1.0]heptane analogues of the glycosidase inhibitor galacto-validamine, (1R*,2S,3S,4S,5S,6S*)-5-amino-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3,4-triol, have been synthesized in 13 steps from 2,3,4,6-tetra-O-benzyl-D-galactose. The inhibitory activities of the two conformationally restricted amines, and their corresponding acetamides, were measured against commercial alpha-galactosidase enzymes from coffee bean and E. coli. The activity of the glycosyl hydrolase family GH27 enzyme (coffee bean) was competitively inhibited by the 1R,6S-amine (7), a binding interaction that was characterized by a K(i) value of 0.541 microM. The GH36 E. coli alpha-galactosidase exhibited a much weaker binding interaction with the 1R,6S-amine (IC(50)= 80 microM). The diastereomeric 1S,6R-amine (9) bound weakly to both galactosidases, (coffee bean, IC(50)= 286 microM) and (E. coli, IC(50)= 2.46 mM).
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By Ellen from European - 2017.10.25 15:53
This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
By Edwina from El Salvador - 2017.03.28 16:34
