2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile CAS: 1240948-72-4
Catalog Number | XD93712 |
Product Name | 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile |
CAS | 1240948-72-4 |
Molecular Formula | C11H6ClFN2 |
Molecular Weight | 220.63 |
Storage Details | Ambient |
Product Specification
Appearance | White powder |
Assay | 99% min |
2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile is a chemical compound with various potential applications in medicinal chemistry and drug discovery. Its unique structural features and properties make it a valuable building block for the synthesis of biologically active molecules and the development of new pharmaceutical compounds.This compound's chloro and fluorophenyl substituents contribute to its lipophilicity, allowing it to interact effectively with hydrophobic regions of target proteins or receptors. Such interactions are crucial in drug design, as they can enhance the compound's affinity and selectivity for the target, which in turn improves its potential therapeutic activity.The carbonitrile group in 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile offers additional synthetic and medicinal advantages. It serves as a versatile functional group that can undergo various transformations, such as hydrolysis or substitution reactions, enabling the introduction of different chemical entities and modifications to the compound's structure. This flexibility is particularly valuable in medicinal chemistry, where structure-activity relationship (SAR) studies help to optimize the compound's pharmacological properties.In pharmaceutical research, this compound can be used as a starting material for the synthesis of diverse derivatives. Through the incorporation of different functional groups or substitutions, chemists can explore the impact of structural variations on the compound's biological activity and selectivity. This enables the creation of focused libraries of compounds for screening in drug discovery programs, enhancing the chances of identifying potential lead compounds.Furthermore, the presence of the carbonitrile group allows for potential metabolic stability enhancements. The introduction of this group can impact the compound's susceptibility to enzymatic degradation and increase its half-life in the body, potentially improving its effectiveness as a drug candidate.In summary, 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile is a versatile compound with significant potential in medicinal chemistry and pharmaceutical research. Its unique structural features, such as the chloro and fluorophenyl substituents and the carbonitrile group, contribute to its interactions with target proteins, flexibility in synthetic modifications, and potential stability enhancements. By utilizing this compound as a building block, researchers can explore its biological activity, optimize its pharmacological properties, and contribute to the development of innovative medications for various diseases and conditions.