2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6
| Catalog Number | XD90961 |
| Product Name | 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one |
|
CAS |
1044871-04-6 |
|
Molecular Formula |
C24H29N3O4 |
|
Molecular Weight |
423.5 |
| Storage Details | |
| Harmonized Tariff Code |
Product Specification
| Appearance | |
| Assay | |
| Boiling point | 612.6±65.0 °C(Predicted) |
| Density | 1.25±0.1 g/cm3(Predicted) |
| Acidity coefficient | (pKa)9.54±0.20(Predicted) |
RVX-297 is a highly potent, orally active BET inhibitor selective for BD2. The IC50s of RVX-297 for BRD2(BD2), BRD3(BD2), and BRD4(BD2) were 0.08, 0.05, and 0.02 μM, respectively. RVX-297 inhibits the expression of various immune cell inflammatory genes. Efficacy of RVX-297 in preclinical models of acute inflammation and autoimmunity.
Close
