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1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent CAS:887144-97-0

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Catalog Number: XD94690
Cas: 887144-97-0
Molecular Formula: C10H10F3IO
Molecular Weight: 330.09
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Product Tags

Catalog Number XD94690
Product Name 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
CAS 887144-97-0
Molecular Formula C10H10F3IO
Molecular Weight 330.09
Storage Details Ambient

 

Product Specification

Appearance White powder
Assay 99% min

 

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, commonly known as Togni's reagent, is a highly versatile and powerful oxidizing agent in organic synthesis. Its unique structure, containing a benziodoxole moiety, gives it the ability to undergo various redox reactions, making it an indispensable tool for synthetic chemists.One significant effect of Togni's reagent is its ability to introduce trifluoromethyl groups into organic molecules. Trifluoromethyl groups are highly desirable in drug discovery and agrochemical industries due to their unique physicochemical properties, such as increased lipophilicity and metabolic stability. Togni's reagent acts as a convenient and efficient source of trifluoromethyl groups, enabling the synthesis of new compounds with enhanced properties.Moreover, Togni's reagent is widely used in the synthesis of heterocyclic compounds. By reacting with a range of nucleophiles, such as amines or alcohols, it can efficiently transform simple compounds into complex heterocycles. These heterocyclic molecules often exhibit interesting biological activities and find applications in the pharmaceutical industry.Togni's reagent also plays an essential role in oxidative transformations. It can oxidize various functional groups, such as alcohols, phenols, thiols, and even unactivated carbon-hydrogen bonds, to yield valuable products. This oxidative capability makes it a versatile tool for the controlled modification of organic molecules, allowing chemists to access a wide array of functionalized compounds.Furthermore, Togni's reagent is employed in the synthesis of materials with unique properties. Its ability to introduce trifluoromethyl groups can modify the physical and chemical characteristics of polymers, leading to improved thermal stability, solubility, and electrical properties. This has applications in materials science, including the design of advanced materials for electronics and energy storage devices.It is worth noting that Togni's reagent should be handled with caution due to its high reactivity and potential toxicity. Safety procedures, including the use of appropriate protective equipment, should be followed when working with this compound. Additionally, it should be stored and disposed of according to safety regulations to minimize any potential risks.In conclusion, 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Togni's reagent, is a versatile oxidizing agent with significant effects in organic synthesis. Its ability to introduce trifluoromethyl groups, facilitate heterocyclic synthesis, and perform selective oxidative transformations makes it an invaluable tool for the creation of new compounds and materials. However, proper safety measures should always be observed when working with this powerful reagent.


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    1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent CAS:887144-97-0