100% Original Beta-D-Glucose Pentaacetate - N-(2-Aminoethyl) morpholine Cas:2038-03-1 99% Colorless to yellow liquid – XD BIOCHEM
100% Original Beta-D-Glucose Pentaacetate - N-(2-Aminoethyl) morpholine Cas:2038-03-1 99% Colorless to yellow liquid – XD BIOCHEM Detail:
| Catalog Number | XD90061 |
| Product Name | N-(2-Aminoethyl)morpholine |
| CAS | 2038-03-1 |
| Molecular Formula | C6H14N2O |
| Molecular Weight | 130.19 |
| Storage Details | Ambient |
Product Specification
| Appearance | Colorless to yellow liquid |
| Assay | 99% min |
| Storage Temp | Store at RT |
| Density | 0.992 g/mL at 25 C(lit.) |
| Refractive index | n20/D 1.476(lit.) |
| Water solubility | Soluble |
| Vapor pressure | 0.289mmHg at 25 C |
Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.
The secretory isozyme of human carbonic anhydrase (hCA, EC 4.2.1.1), hCA VI, has been cloned, expressed, and purified in a bacterial expression system. The kinetic parameters for the CO(2) hydration reaction proved hCA VI to possess a k(cat) of 3.4 x 10(5)s(-1) and k(cat)/K(M) of 4.9 x 10(7)M(-1)s(-1) (at pH 7.5 and 20 degrees C). hCA VI has a significant catalytic activity for the physiological reaction, of the same order of magnitude as the ubiquitous isoform CA I or the transmembrane, tumor-associated isozyme CA IX. A series of amino acids and amines were shown to act as CA VI activators, with variable efficacies. l-His, l-Trp, and dopamine showed weak CA VI activating effects (K(A)s in the range of 21-42 microM), whereas d-His, d-Phe, l-DOPA, l-Trp, serotonin, and some pyridyl-alkylamines were better activators, with K(A)s in the range of 13-19 microM. The best CA VI activators were l-Phe, d-DOPA, l-Tyr, 4-amino-l-Phe, and histamine, with K(A)s in the range of 1.23-9.31 microM. All these activators enhance k(cat), having no effect on K(M), participating thus in the rate determining step in the catalytic cycle, the proton transfer reactions between the enzyme active site and the environment.
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By Prudence from Mombasa - 2017.11.20 15:58
